We sell Renew, and this article used to be considerably more enthusiastic about it. It has been rewritten because it was making a claim this site had already decided not to make anywhere else, and nobody noticed because the blog lived somewhere the rest of our copy review never reached.
What is actually being claimed
Renew is what the industry calls an HGH secretagogue: it does not contain growth hormone, it is sold on the idea of encouraging your body to release more of its own.
That distinction matters more than anything else on this page. Human growth hormone itself is a prescription drug. In the United States it can be prescribed for a short list of specific conditions, and selling or prescribing it for anti-aging is not lawful. Any product on a shop shelf is, necessarily, not that.
The real finding underneath, and the leap from it
There is a genuine observation here, which is why the category exists.
Certain amino acids, arginine in particular, can produce a measurable short-term rise in growth hormone. That was established decades ago and is not in dispute.
Three things get left out when it becomes marketing:
The doses are not comparable. The studies showing a clear effect generally used large amounts, often given intravenously or as several grams at once on an empty stomach. A capsule blend is a different proposition.
A transient rise is not the same as a sustained change. Growth hormone is released in pulses, mostly at night. Nudging one pulse is not the same as changing your hormonal profile.
Nothing downstream follows automatically. This is the important one. Even granting a rise in the hormone, that is a measurement, not a benefit. The step from "this moved a number" to "therefore skin, sleep, memory, heart, bone density and body composition all improve" has not been demonstrated, and it is exactly the step the previous version of this page took in a single sentence.
We went through this pattern in detail on our own supplier's research in Reading the Research.
What is actually in it
Amino acids including L-arginine and L-glutamine, GABA, and herbal extracts including astragalus root.
Two notes worth having:
GABA is the most interesting ingredient and not for the reason given. It is included in these formulas because of the growth-hormone link, but GABA taken by mouth crosses into the brain poorly, and the better-supported reason people report liking it is a mild calming effect. If it helps you sleep, that is worth something on its own terms, and sleep is genuinely when most growth hormone is released. That is a more modest and more defensible chain than the one the marketing draws.
The full panel is on the product page, with amounts. Our ingredient amounts come from the label rather than being derived, which matters on a supplement.
What we will not tell you
The previous version of this page listed improved brain function, skin, sleep, immune support, cardiac function, metabolism, bone density and sexual well-being, and described them as proven.
It also added claims about heart disease risk and blood lipids further down. None of that is supportable, and this site had already decided not to make that claim. Our record of Partner.Co's approved claims lists the Renew growth hormone framing among the things we do not use, with a reason. The blog was contradicting our own position, and this is the correction.
Who might reasonably try it
Someone who wants an amino acid and GABA blend, is interested in the sleep angle, and is not expecting it to alter how they age. That is a narrower proposition than the marketing and it is the one the evidence supports.
If you take any prescription medication, are pregnant or nursing, or have any endocrine condition, this is a conversation with a doctor before it is a purchase.
We also publish our review of Nutrifii Moa and Vináli from the same range.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
More on this subject: Everyday Nutrition